ISBN-13
978-0323083300
Commonly known as the #1 bench reference for practising microbiologists and an excellent textual content material for faculty college students in scientific laboratory science packages, Bailey & Scott’s Diagnostic Microbiology, 13th Edition helps you develop and refine the skills you need for environment friendly laboratory testing. In-depth information is useful and easily accessible, with step-by-step instructions for the entire procedures. This model choices higher than 20 NEW chapters plus updated supplies on the newest advances and the latest developments in scientific microbiology. Written by skilled Dr. Patricia Tille, this conventional reference addresses the issues and factors most associated to you and your success on the job.
- Arms-on procedures embody step-by-step instructions, full-shade photos, and anticipated outcomes, serving to you acquire additional right outcomes.
- Case analysis present the choice to make use of your experience in a variety of diagnostic eventualities and help improve your alternative-making and vital contemplating experience.
- Genera and Species to be Considered bins highlight all the organisms to be talked about in each chapter, along with the current title of the species along with any earlier names.
- Scholar belongings on Evolve enhance your finding out with overview questions and procedures.
- Helpful, easy-to-study tables summarize key information.
- Detailed, full-shade illustrations assist comprehension and help you visualize concepts.
- A glossary of phrases is found behind the e-e-book for quick reference.
- NEW! Learning targets begin each chapter, supplying you with a measurable closing end result to achieve by the ending the material.
- NEW! Consider questions on the Evolve companion website are tied to finding out targets, and enhance your understanding and retention of chapter content material materials.
- NEW! Reader-nice chapters cowl groups of related organisms fairly than addressing , along with the parasitology, mycology, and virology chapters.
Chapter 11: Guidelines of Antimicrobial Movement and Resistance
Test Bank
MULTIPLE CHOICE
1. Antimicrobial brokers that inhibit bacterial progress nonetheless normally do not kill the organism are generally called:
a. bactericidal.
b. antibiotic.
c. bacteriostatic.
d. antagonistic.
ANS: C
Bacteriostatic means the inhibition of bacterial progress, whereas bactericidal means killing bacterial progress.
REF: 152 OBJ: Stage: Data
2. Antimicrobial brokers that usually kill objective organisms are talked about to be:
a. bactericidal.
b. antibiotic.
c. bacteriostatic.
d. antagonistic.
ANS: A
Bactericidal means killing bacterial progress, whereas Bacteriostatic means the inhibition of bacterial progress.
REF: 152 OBJ: Stage: Data
3. Antimicrobial resistance ensuing from the standard genetic, structural, or physiologic state of a microorganism is named ________ resistance.
a. intrinsic
b. inherent
c. microorganism-mediated
d. scientific
ANS: A
Intrinsic resistance is taken under consideration to be a pure and persistently inherited attribute that is associated to the overwhelming majority of strains that characterize a particular bacterial group, genus, or species.
REF: 160 OBJ: Stage: Data
4. Antibiotic resistance ensuing from altered cell physiologic development introduced on by changes in a microorganism’s common genetic make-up is called __________ resistance.
a. intrinsic
b. inherent
c. acquired
d. environmentally mediated
ANS: C
Acquired-resistance mechanisms are all genetically encoded; subsequently the methods for acquisition are those that allow for gene change or commerce. Resistance is also acquired by genetic mutation, gene-change mechanisms, or a mixture of mutational and gene-change events.
REF: 160 OBJ: Stage: Data
5. Staphylococcus aureus is a gram-constructive organism that produces the enzyme beta-lactamase, which renders certain forms of antibiotics inactive. The mode of movement that is prevented in certain antibiotics delicate to this enzyme is:
a. cell wall synthesis.
b. protein synthesis to the 30S ribosomal subunit.
c. protein synthesis to the 50S ribosomal subunit.
d. deoxyribonucleic acid (DNA) synthesis.
ANS: A
Beta-lactamases open the beta-lactam ring of the drug, and the altered development prohibits subsequent environment friendly binding to penicillin-binding proteins (PBPs), enabling cell wall synthesis to proceed.
REF: 161 OBJ: Stage: Utility
6. The mechanism of acquired, extreme-stage resistance to vancomycin contains:
a. enzymatic destruction of the antibiotic.
b. altered antibiotic targets.
c. decreased intracellular uptake of the drug.
d. manufacturing of altered cell wall precursors that do not bind the antibiotic with sufficient avidity.
ANS: D
The mechanism contains altered cell wall precursors that do not bind vancomycin with sufficient avidity to allow the inhibition of peptidoglycan-synthesizing enzymes. The altered targets are readily included into the cell wall, enabling synthesis to progress as common.
REF: 163 OBJ: Stage: Data
7. Mycoplasmas are organisms with out cell partitions. Which antimicrobial brokers might be ineffective in treating infections involving this bacterium?
a. Tetracycline
b. Aminoglycosides
c. Penicillin
d. Rifampin
ANS: C
Penicillin, amongst others, is an antibiotic that acts by binding the enzymes which could be involved in cell wall synthesis. Because of mycoplasmas haven’t got cells partitions, all these antibiotics normally will not be environment friendly.
REF: 156 OBJ: Stage: Utility
8. Klebsiella spp. have been isolated from a sputum sample, and susceptibility testing was carried out. The isolates have been delicate to a lot of antibiotics; nonetheless, they’ve been proof in opposition to ampicillin. Which certainly one of many following statements explains this discrepancy?
a. The ampicillin disk is most likely expired.
b. Because of Klebsiella spp. must be delicate to ampicillin, a technical error is in cost.
c. Ampicillin inhibits cell wall synthesis. In addition to, because of Klebsiella spp. haven’t got a cell wall, they should not have been examined for ampicillin.
d. No discrepancy is present; Klebsiella spp. are normally proof in opposition to ampicillin.
ANS: D
Klebsiella spp. are normally resistant attributable to intrinsic resistance.
REF: 160 OBJ: Stage: Downside Fixing
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